T cells from common colds cross-protect against infection with SARS-CoV-2

"Our study provides the clearest evidence to date that T cells induced by common cold coronaviruses play a protective role against SARS-CoV-2 infection."

Professor Ajit Lalvani, Director of the NIHR Respiratory Infections Health Protection Research Unit

“Being exposed to the SARS-CoV-2 virus doesn’t always result in infection, and we’ve been keen to understand why. We found that high levels of pre-existing T cells, created by the body when infected with other human coronaviruses like the common cold, can protect against COVID-19 infection.”

Dr Rhia Kundu, first author of the study, from Imperial’s National Heart & Lung Institute

Current vaccines do not induce an immune response to these internal proteins.